Xylazine Hydrochloride

Synonyms: Bay-Va-1470; Hidrocloruro de xilazina; Ksylatsiinihydrokloridi; Xilazin-hidroklorid; Xylazine, chlorhydrate de; Xylazin-hydrochlorid; Xylazinhydroklorid; Xylazini hydrochloridum.
Cyrillic synonym: Ксилазина Гидрохлорид.

Chemical information

Chemical formula: C12H16N2S, HCl = 256.8.
CAS — 23076-35-9.


In US. Eur. includes for veterinary use only.

Ph. Eur. 6.2

(Xylazine Hydrochloride for Veterinary Use; Xylazine Hydrochloride BP(Vet) 2008). A white or almost white, crystalline, hygroscopic powder. Freely soluble in water and in dichloromethane; very soluble in methyl alcohol. A 10% solution in water has a pH of 4.0 to 5.5. Store in airtight containers. Protect from light.

USP 31

(Xylazine Hydrochloride). Colourless to white crystals. Sparingly soluble in acetone, in methyl alcohol, and in dilute acid; insoluble in dilute alkali. A 1% solution in water has a pH of 4.0 to 6.0. Store in airtight containers at a temperature of 25°, excursions permitted between 15° and 30°.


Xylazine is a sedative, analgesic, and muscle relaxant used in veterinary medicine. The hydrochloride is used similarly. Abuse has been reported.

Adverse effects.

Reports1-5 of toxicity and abuse associated with xylazine. Bradycardia, hypotension, and coma were associated with the self-administration of 200 mg of xylazine. Treatment was supportive.1
1. Samanta A, et al. Accidental self administration of xylazine in a veterinary nurse. Postgrad Med J 1990; 66: 244–5
2. Mittleman RE, et al. Xylazine toxicity—literature review and report of two cases. J Forensic Sci 1998; 43: 400–2
3. Hoffmann U, et al. Severe intoxication with the veterinary tranquilizer xylazine in humans. J Anal Toxicol 2001; 25: 245–9
4. Capraro AJ, et al. Severe intoxication from xylazine inhalation. Pediatr Emerg Care 2001; 17: 447–8
5. Elejalde JI, et al. Drug abuse with inhalated xylazine. Eur J Emerg Med 2003; 10: 252–3.
Published May 08, 2019.