The wild lettuce, Lactuca virosa (Compositae), has been given in herbal medicine as a sedative and antitussive. The dried latex extract (lactucarium; lettuce opium) is also used.

Multi-ingredient: Canad.: Sirop Cocillana Codeine; Sirop Cocillana Compose; S.Afr.: Choats Extract of Lettuce Cough Mixture; UK: Anased; Antibron; Gerard House Somnus; HRI Night; Kalms Sleep; Quiet Life; Quiet Nite; Slumber; Unwind Herbal Nytol; Venez.: Cerylana.