Vinyl Chloride

(USAN, rINN)
Vinyl Chloride Chemical formula

Chemical information

Cloruro de vinilo; VCM; Vinilo, cloruro de; Vinyl Chloride Monomer; Winylu chlorek. Chloroethylene.
Chemical formula: C2H3Cl = 62.50.
CAS — 75-01-4.

Profile

Vinyl chloride is used in the manufacture of polyvinyl chloride (PVC) and other vinyl polymers. Occupational exposure to vinyl chloride in polymerisation plants has been associated with acroosteolysis, especially in the terminal phalanges of the fingers, a condition resembling Raynaud’s phenomenon, and sclerodermatous skin changes. Liver damage and hepatic angiosarcoma, splenomegaly, thrombocytopenia, impaired respiratory function, and chromosomal abnormalities have also occurred.
1. Infante PF, et al. Genetic risks of vinyl chloride. Lancet 1976; i: 734–5
2. Black CM, et al. Genetic susceptibility to scleroderma-like syndrome induced by vinyl chloride. Lancet 1983; i: 53–5
3. Piratsu R, et al. La mortalità dei produttori di cloruro di vinile in Italia. Med Lav 1991; 82: 388–423
4. Riordan SM, et al. Vinyl chloride related hepatic angiosarcoma in a polyvinyl chloride autoclave cleaner in Australia. Med J Aust 1991; 155: 125–8
5. Mur JM, et al. Spontaneous abortion and exposure to vinyl chloride. Lancet 1992; 339: 127–8
6. McLaughlin JK, Lipworth L. A critical review of the epidemiologic literature on health effects of occupational exposure to vinyl chloride. J Epidemiol Biostat 1999; 4: 253–75.
Published May 08, 2019.