Vinpocetine

(USAN, rINN)
Vinpocetine Chemical formula
Synonyms: AY-27255; Ethyl Apovincaminate; Ethyl Apovincaminoate; RGH4405; Vinpocetin; Vinpocetina; Vinpocétine; Vinpocetinum; Vinposetiini. Ethyl (3
Cyrillic synonym: Винпоцетин.

💊 Chemical information

Chemical formula: C22H26N2O2 = 350.5.
CAS — 42971-09-5.
ATC — N06BX18.
ATC Vet — QN06BX18.

Pharmacopoeias.

In Eur..

Ph. Eur. 6.2

(Vinpocetine). A white or slightly yellow, crystalline powder. Practically insoluble in water; soluble in dichloromethane; slightly soluble in anhydrous alcohol.

💊 Profile

Vinpocetine is a derivative of vincamine (above) that has been given orally in cerebrovascular disorders and dementia. Good evidence to support its use in cognitive impairment is lacking.
1. Grandt R, et al. Vinpocetine pharmacokinetics in elderly subjects. Arzneimittelforschung 1989; 39: 1599–1602
2. Blaha L, et al. Clinical evidence of the effectiveness of vinpocetine in the treatment of organic psychosyndrome. Hum Psychopharmacol Clin Exp 1989; 4: 103–11
3. Bereczki D, Fekete I. A systematic review of vinpocetine therapy in acute ischaemic stroke. Eur J Clin Pharmacol 1999; 55: 349–52
4. Szatmari SZ, Whitehouse PJ. Vinpocetine for cognitive impairment and dementia. Available in The Cochrane Database of Systematic Reviews; Issu
1. Chichester: John Wiley; 2003 (accessed 31/03/06)
5. Kemény V, et al. Acute and chronic effects of vinpocetine on cerebral hemodynamics and neuropsychological performance in multi-infarct patients. J Clin Pharmacol 2005; 45: 1048–54.

💊 Preparations

Proprietary Preparations

Arg.: Cavinton†; Braz.: Vicog; Cz.: Cavinton; Vicebrol; Ger.: Cavinton†; Hung.: Cavinton; Pol.: Cavinton; Vicebrol; Vinpoton; Port.: Cavinton; Ultra-Vinca; Vipocem; Rus.: Cavinton (Кавинтон); Telectol (Телектол); Singapore: Cavinton; Thai.: Cavinton; Vinpocen. Multi-ingredient: Rus.: Vinpotropile (Винпотропил).
Published May 08, 2019.