Veratrine

(BAN, USAN, rINN)

💊 Chemical information

Veratriini; Veratrin; Veratrina; Veratrinum.
CAS — 8051-02-3 (veratrine mixture); 71-62-5 (veratrine amorphous); 62-59-9 (veratrine crystallised, cevadine).

Description.

Veratrine is a mixture of alkaloids from the dried ripe seeds of Schoenocaulon officinale (Liliaceae) (sabadilla). Veratrine should be distinguished from protoveratrines obtained from veratrum.

💊 Adverse Effects, Treatment, and Precautions

Veratrine resembles aconite in its action on the peripheral nerve endings and poisoning should be treated similarly. It is an intense local irritant and has a powerful direct stimulating action on all muscle tissues. It has a violent irritant action on mucous membranes, even in minute doses, and must be handled with great care. When ingested it causes violent vomiting, purging, an intense burning sensation in the mouth and throat, and general muscular weakness.

💊 Uses and Administration

Veratrine should not be used internally. It was formerly applied externally for its analgesic properties and as a parasiticide, especially for head lice, but even when used in this way there is danger of systemic poisoning from absorption.
Published May 08, 2019.