Valtrate

(pINN)
Synonyms: Valtrato; Valtratum. 4-Acetoxymethyl-1,6-di-isovaleryloxy1,6,7,7a-tetrahydrocyclopenta[c]pyran-7-spiro-2′-oxiran.
Cyrillic synonym: Вальтрат.

💊 Chemical information

Chemical formula: C22H30O8 = 422.5.
CAS — 18296-44-1.

💊 Profile

Valepotriates are epoxy-iridoid esters, isolated from valerian (see below). They include acevaltrate, didrovaltrate, and valtrate. On prolonged storage and drying they are hydrolysed to yield isovaleric acid. A mixture stated to contain acevaltrate, didrovaltrate, and valtrate has been used as a sedative and as an anxiolytic. Concern has been expressed over the potential toxicity of valepotriates which have been reported to have cytotoxic properties in vitro.

💊 Preparations

Proprietary Preparations

Austria: Valmane; Gr.: Valmane. Multi-ingredient: Arg.: SDN 200.
Published May 08, 2019.