Ulinastatin

(rINN)
Synonyms: Ulinastatina; Ulinastatine; Ulinastatinum; Urinastatin.
Cyrillic synonym: Улинастатин.

💊 Chemical information

CAS — 80449-31-6; 80449-32-7.

Pharmacopoeias.

In Jpn.

💊 Profile

Ulinastatin is a glycoprotein proteolytic enzyme inhibitor isolated from human urine. It has been given by slow intravenous injection or by intravenous infusion in acute pancreatitis and in acute circulatory insufficiency.
1. Ohwada M, et al. New endoscopic treatment for chronic pancreatitis, using contrast media containing ulinastatin and prednisolone. J Gastroenterol 1997; 32: 216–21
2. Sugita T, et al. Effect of a human urinary protease inhibitor (Ulinastatin) on respiratory function in pediatric patients undergoing cardiopulmonary bypass. J Cardiovasc Surg 2002; 43: 437–40
3. Tsujino T, et al. Ulinastatin for pancreatitis after endoscopic retrograde cholangiopancreatography: a randomized, controlled trial. Clin Gastroenterol Hepatol 2005; 3: 376–83.

💊 Preparations

Proprietary Preparations

Jpn: Miraclid.
Published May 08, 2019.