Tannic Acid

(rINN)

💊 Chemical information

Acide tannique; Acidum Tannicum; Gallotannic Acid; Garvsyra; Gerbstoff; Kwas taninowy; Tánico, ácido; Tanin; Tanina; Taninas; Tann. Acid; Tanniini (Parkkihappo); Tannin; Tanninum.
CAS — 1401-55-4.

Pharmacopoeias.

In Eur., Jpn, and US.

Ph. Eur. 6.2

(Tannic Acid). A mixture of esters of glucose with gallic acid and 3-galloylgallic acid. A yellowish-white or slightly brown amorphous light powder or shiny plates. Very soluble in water; freely soluble in alcohol, in acetone, and in glycerol (85%); practically insoluble in dichloromethane. Protect from light.

USP 31

(Tannic Acid). A tannin usually obtained from nutgalls, the excrescences produced on the young twigs of Quercus infectoria and allied species of Quercus, from the seed pods of tara (Caesalpinia spinosa), or from the nutgalls or leaves of sumac (any of genus Rhus). Amorphous powder, glistening scales, or spongy masses, varying in colour from yellowish-white to light brown. Is odourless or has a faint, characteristic odour. Very soluble in water, in alcohol, and in acetone; freely soluble in diluted alcohol; slightly soluble in dehydrated alcohol; practically insoluble in chloroform, in ether, in petroleum spirit, and in benzene; soluble 1 in about 1 of warm glycerol. Store in airtight containers. Protect from light.

💊 Profile

Tannic acid has been used as an astringent for the mucous membranes of the mouth and throat, and in suppositories for the treat ment of haemorrhoids. It is an ingredient in a number of dermatological preparations. Former uses of tannic acid include application to burns, addition to barium sulfate enemas to improve the quality of radiological pictures of the colon, and as an ingredient of ‘Universal Antidote’. However, tannic acid has been associated with liver toxicity, sometimes fatal.

Tattoo removal.

Although tannic acid may be used by plastic surgeons and dermatologists to produce a controlled partialthickness burn in tattoo removal1 it has been pointed out that in unskilled or amateur hands this procedure has resulted in full thickness burns requiring skin grafting to obtain satisfactory healing.2
1. Mercer NSG, Davies DM. Tattoos. BMJ 1991; 303: 380
2. Scott M, Ridings P. Tattoos. BMJ 1991; 303: 720.

💊 Preparations

Proprietary Preparations

Ger.: Tannosynt; Spain: Tanagel Papeles. Multi-ingredient: Austral.: SM-33; Austria: Haemanal; Paradenton; Belg.: Hemorhinol; Braz.: Lacto Vagin†; Canad.: Ta n a c; Fr.: Allerbiocid S†; Eau Precieuse; HEC; Ger.: Bioget†; Tannolil†; Gr.: Oulogram; Irl.: Phytex; Israel: Rectozorin; Ital.: Blefarolin; Neo Emocicatrol; Philipp.: Zilactin; Pol.: Acifungin; Salumin; Rus.: Contraceptin T (Контрацептин Т); NeoAnusol (Нео-анузол); Singapore: HEC†; Spain: Antihemorroidal; Depurativo Richelet; Dextricea; Sabanotropico; Tanagel; Tangenol†; Switz.: HEC; Tanno-Hermal; UK: Colsor; Phytex; TCP; USA: Dermasept Antifungal; Orasept; Outgro; Tanac; Tanac Dual Core.
Published May 08, 2019.