Satavaptan
(rINN)
Synonyms: Satavaptán; Satavaptanum; SR-121463 (satavaptan); SR-121463B (morpholin-4-yl)ethoxy]-2′-oxo-1′,2′-dihydrospiro[cyclohexane1:3′-indole]-1′-yl}sulfonyl)-3-methoxybenzamide.
Cyrillic synonym: Сатаваптан.
Chemical information
Chemical formula: C33H45N3O8S = 643.8.
CAS — 185913-78-4 (satavaptan); 308145-17-7 (satavaptan phosphate).
Profile
Satavaptan is a selective vasopressin V2-receptor antagonist under investigation for the treatment of hyponatraemia in the syndrome of inappropriate antidiuretic hormone secretion.
◊ References.
1. Soupart A, et al. Successful long-term treatment of hyponatremia in syndrome of inappropriate antidiuretic hormone secretion with satavaptan (SR121463B), an orally active nonpeptide vasopressin V -receptor antagonist. Clin J Am Soc Nephrol 2006; 1: 1154–60.
Published May 08, 2019.