Sassafras Oil


💊 Chemical information

Oleum Sassafras; Sasafrás, aceite esencial de.

💊 Profile

Sassafras oil is a volatile oil distilled from the root or root bark of Sassafras albidum (Lauraceae), or from the wood of certain species of Ocotea (Lauraceae). It contains safrole. Sassafras oil has rubefacient properties and was formerly used as a pediculicide. Neither sassafras nor the oil should be taken internally; the use of herb teas of sassafras may lead to a large dose of safrole. The use of safrole in foods has been banned because of carcinogenic and hepatotoxic risks. The use of safrole in toilet preparations is also controlled.


A 47-year-old woman experienced ‘shakiness’, vomiting, anxiety, tachycardia, and raised blood pressure after ingestion of a potentially fatal dose of sassafras oil (5 mL). She was given activated charcoal and symptomatic management.1
1. Grande GA, Dannewitz SR. Symptomatic sassafras oil ingestion. Vet Hum Toxicol 1987; 29: 447.

💊 Preparations

Proprietary Preparations

Multi-ingredient: Arg.: Inhalador Medex; Austral.: Urinase†; Zam-Buk†; Cz.: Stopangin; Fr.: Vegebom; Indon.: Thymcal; Rus.: Stopangin (Стопангин); S.Afr.: Moultons Pain Paint; Zam-Buk†; Spain: Linimento Klari†.
Published May 08, 2019.