Royal Jelly

Synonyms: Apilak; Jalea real; Queen Bee Jelly.
Cyrillic synonym: Маточное Молочко.

💊 Chemical information

CAS — 8031-67-2.

💊 Profile

Royal jelly is a milky-white viscid secretion from the salivary glands of the worker honey bee, Apis mellifera (Apidae); it is essential for the development of queen bees. Royal jelly has been used as a nutritional supplement, but of the many and diverse claims made for its therapeutic value, none has been substantiated. Royal jelly is also included in some cosmetic preparations for its supposed beneficial effect on skin tissue. Hypersensitivity reactions have been reported.


There were 14 reports of suspected adverse effects (10 considered serious) involving bee products such as royal jelly, propolis, and bee pollen reported to the Canadian health authorities (Health Canada) between January 1998 and October 2004.1 Anaphylactoid reactions2 and acute severe exacerbations of asthma3-6 (one fatal4) have occurred in atopic individuals who took royal jelly.
1. Health Canada. Products derived from bees: serious adverse reactions. Can Adverse React News 2005; 15 (2): 2–3. Also available at: medeff/carn-bcei_v15n2-eng.pdf (accessed 08/08/08
2. Takahama H, Shimazu T. Food-induced anaphylaxis caused by ingestion of royal jelly. J Dermatol 2006; 33: 424–6
3. Thien FCK, et al. Royal jelly-induced asthma. Med J Aust 1993; 159: 639
4. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994; 160: 44
5. Peacock S, et al. Respiratory distress and royal jelly. BMJ 1995; 311: 1472
6. Thien FCK, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996; 26: 216–22.

💊 Preparations

Proprietary Preparations

Fr.: Apiserum; Ital.: Alvear; Biogel; Biovital; Clinvit; Gelamel†; Novel Jelly†; Pa-Real; Ritmogel; Roburvit; Telergon II; Rus.: Apilac (Апилак); UK: Biobees; Regina Royal One Hundred; Rojema. Multi-ingredient: Fr.: Gintonal†; Pollen Royal†; Ger.: Peking Royal Jelly N†; Indon.: Hemaviton Energy Drink; Hemaviton Jreng; Neo Hormoviton; Neo Hormoviton Greng; Ital.: Alvear con Ginseng; Apergan; Api Baby; Apiserum con Telergon 1; Apistress; Bebimix; Bio-200; Bioton; Biotrefon Plus; Eurogel; Fon Wan Ginsenergy; Fosfarsile Forte; Fosfarsile Junior; FourTon; Granvit; Longevital; Neoplus; Nerex; Nutrigel†; Ottovis; Pollingel; Provitamin A-E; Ribovir; Royal E; Mex.: Supravital; Philipp.: Jamieson Total Energy; Thai.: Multilim RG; UK: Regina Royal Concorde; Regina Royal Five.
Published May 08, 2019.