Potassium Chlorate

(USAN)

💊 Chemical information

Clorato potásico; Kalium Chloricum; Potassii Chloras; Potasu chloran.
Chemical formula: KClO3 = 122.5.
CAS — 3811-04-9.

Handling and storage.

Potassium chlorate is unstable and, in contact with organic or readily oxidisable substances such as charcoal, phosphorus, or sulfur it is liable to explode especially if heated or subjected to friction or percussion. It should not be allowed to come into contact with matches or surfaces containing phosphorus compounds. Reasonable steps should be taken before supplying potassium chlorate to ensure that it will not be used for the illicit preparation of explosives or fireworks.

💊 Profile

Potassium chlorate has been used as an astringent, usually as a mouthwash or gargle. Concentrated solutions are irritant. Acute poisoning from ingestion requires prompt symptomatic treatment. Symptoms include nausea, vomiting, diarrhoea, abdominal pain, haemolytic anaemia, haemorrhage, methaemoglobinaemia, hyperkalaemia, and renal failure. There may be liver damage and central effects with convulsions and coma. Gastric lavage should be considered within 1 hour of ingestion of potassium chlorate; activated charcoal is also recommended by some. If methaemoglobinaemia is severe, patients may require exchange transfusion with whole blood. Several authorities consider that methylthioninium chloride should be given intravenously if methaemoglobinaemia is greater than 30%, although some have advised against such use for fear of converting chlorate to the more toxic hypochlorite.

💊 Preparations

Proprietary Preparations

Multi-ingredient: Canad.: Fletchers Sore Mouth Medicine; Spain: Edifaringen; Faringenilo; Solurrinol.
Published May 08, 2019.