Potassium Aminobenzoate

(USAN)
Potassium Aminobenzoate Chemical formula

💊 Chemical information

Aminobenzoate Potassium; Aminobenzoato potásico. Potassium 4-aminobenzoate.
Chemical formula: C7H6KNO2 = 175.2.
CAS — 138-84-1.

Pharmacopoeias.

In US.

USP 31

(Aminobenzoate Potassium). A white crystalline powder. Very soluble in water; soluble in alcohol; practically insoluble in ether. A 1% solution in water has a pH of about 7, while a 5% solution has a pH of 8.0 to 9.0.

💊 Adverse Effects and Precautions

Anorexia, nausea, fever, and skin rash have been reported. Potassium aminobenzoate should be given with caution to patients with renal impairment. Licensed product information recommends that treatment should be interrupted during periods of fasting, anorexia, or low food intake, to avoid the possible development of hypoglycaemia.

💊 Interactions

Potassium aminobenzoate can inactivate sulfonamides.

💊 Uses and Administration

Potassium aminobenzoate has been used in the treatment of various disorders associated with excessive fibrosis, such as scleroderma and Peyronie’s disease, in usual doses of 12 g daily by mouth in 4 to 6 divided doses. Peyronie’s disease . Variable results have been reported with potassium aminobenzoate in the treatment of Peyronie’s disease,1-3 but evidence from well controlled trials is lacking. It has been suggested that a successful response is more likely if treatment is started in the acute stage.2
1. Gingell JC, Desai KM. Peyronie’s disease. BMJ 1988; 298: 1489–90
2. Mohanty KC, Strachan RG. Peyronie’s disease. BMJ 1989; 298: 254
3. Carson CC. Potassium para-aminobenzoate for the treatment of Peyronie’s disease: is it effective? Tech Urol 1997; 3: 135–9.

💊 Preparations

USP 31: Aminobenzoate Potassium Capsules; Aminobenzoate Potassium for Oral Solution; Aminobenzoate Potassium Tablets.

Proprietary Preparations

Austria: Potaba; Canad.: Potaba; Ger.: Potaba; Gr.: Potaba; UK: Potaba; USA: Potaba.
Published May 08, 2019.