Pinaverium Bromide

(rINN)
Pinaverium Bromide Chemical formula
Synonyms: Bromuro de pinaverio; Pinaverii Bromidum; Pinavérium, Bromure de; Pinaveriumbromid; Pinaveriumbromidi; Pinaveryum Bromür. 4-(6-Bromoveratryl)-4-{2-[2-(6,6-dimethyl-2-norpinyl)ethoxy]ethyl}morpholinium bromide.
Cyrillic synonym: Пинаверия Бромид.

💊 Chemical information

Chemical formula: C26H41Br2NO4 = 591.4.
CAS — 59995-65-2 (pinaverium); 53251-94-8 (pinaverium bromide).
ATC — A0 3AX04.
ATC Vet — QA03AX04.

💊 Profile

Pinaverium bromide is a calcium-channel blocker with some antimuscarinic-like effects. It is used for the relief of gastrointestinal spasm in usual doses of 50 mg orally three times daily at mealtimes.

Effects on the gast

rointestinal tract. Two patients had heartburn and dysphagia after taking pinaverium bromide orally between meals; endoscopy revealed acute oesophageal ulceration, which healed on stopping treatment.1 The manufacturer’s recommendation to take pinaverium bromide during meals was emphasised.
1. André J-M, et al. Ulcères oesophagiens après prise de bromure de pinaverium. Acta Endosc 1980; 10: 289–91.

💊 Preparations

Proprietary Preparations

Arg.: Dicetel; Austria: Dicetel; Belg.: Dicetel; Braz.: Dicetel; Canad.: Dicetel; Chile: Eldicet; Laudil†; Cz.: Dicetel; Fr.: Dicetel; Gr.: Dicetel; Hung.: Dicetel; India: Eldicet; Ital.: Dicetel; Mex.: Dicetel; Zerpyco; Philipp.: Eldicet; Port.: Dicetel; Rus.: Dicetel (Дицетел); Spain: Eldicet; Switz.: Dicetel; Thai.: Dicetel; Turk.: Dicetel; Venez.: Dicetel.
Published May 08, 2019.