Phosphatidyl Choline


💊 Chemical information

Fosfatidilcolina; Phosphatidylcholine.

💊 Profile

Phosphatidyl choline is a phospholipid and a constituent of lecithin. Phosphatidyl choline is an ingredient of preparations that have been promoted for liver disorders, peripheral vascular disorders, hyperlipidaemias, and fat emboli. Some injection preparations of phosphatidyl choline have been promoted for use in cosmetic surgery to remove subcutaneous fat deposits, but this use is not licensed in the UK.

Ulcerative colitis.

Phosphatidyl choline is a component of mucus and plays a key role in mucosal defence. Since a disturbed mucosal barrier is believed to be a factor in the pathogenesis of ulcerative colitis, exogenous phosphatidyl choline has been investigated to improve the protective effects of colonic mucus. Controlled-release oral phosphatidyl choline was beneficial compared with placebo in patients with ulcerative colitis in 2 small short-term studies.1,2
1. Stremmel W, et al. Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. Gut 2005; 54: 966–71
2. Stremmel W, et al. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med 2007; 147: 603–10.

💊 Preparations

Proprietary Preparations

Ital.: Essentiale†; Lipostabil†; Singapore: Hepakur; USA: PhosChol. Multi-ingredient: Arg.: Ikx Gel Reductor; Austral.: Tyroseng†; Ger.: Repithel; India: Livage; Indon.: Liposerin; Ital.: Essaven; Zeroac; Singapore: Memoloba†.
Published May 08, 2019.