Oleander

(BAN, rINN)

💊 Chemical information

Adelfa; Baladre; Common Oleander; Espirradeira; Laurier Rose; Oleanderblätter; Oleandri Folium; Rose Bay.

💊 Profile

The dried leaves of the oleander shrub, Nerium oleander (Apocynaceae), contain cardioactive glycosides, including oleandrin. They have been used in the treatment of heart disorders. The flowers and bark have been used similarly. Toxicity, similar to that seen with digoxin, may occur after ingestion of any part of the plant; fatalities have been reported. Yellow oleander (Thevetia peruviana) also contains cardiac glycosides and exhibits similar toxicity to oleander.

Homoeopathy.

Oleander has been used in homoeopathic medicines under the following names: Nerium oleander; Oleand.

Treatment of adverse effects.

References to the treatment of oleander poisoning or yellow oleander poisoning.
1. Shumaik GM, et al. Oleander poisoning: treatment with digoxinspecific Fab antibody fragments. Ann Emerg Med 1988; 17: 732–5
2. Safadi R, et al. Beneficial effect of digoxin-specific Fab antibody fragments in oleander intoxication. Arch Intern Med 1995; 155: 2121–5
3. Eddleston M, et al. Anti-digoxin Fab fragments in cardiotoxicity induced by ingestion of yellow oleander: a randomised controlled trial. Lancet 2000; 355: 967–72
4. Fonseka MM, et al. Yellow oleander poisoning in Sri Lanka: outcome in a secondary care hospital. Hum Exp Toxicol 2002; 21: 293–5
5. de Silva HA, et al. Multiple-dose activated charcoal for treatment of yellow oleander poisoning: a single-blind, randomised, placebo-controlled trial. Lancet 2003; 361: 1935–8.

💊 Preparations

Proprietary Preparations

Multi-ingredient: Ger.: Miroton.
Published May 08, 2019.