Nitrobenzene

(USAN, rINN)
Nitrobenzene Chemical formula

💊 Chemical information

Aceite de mirbana; Nitrobenceno; Nitrobenzen; Nitrobenzol; Oil of Mirbane.
Chemical formula: C6H5NO2 = 123.1.
CAS — 98-95-3.

💊 Adverse Effects

Nitrobenzene is highly toxic and the ingestion of 1 g may be fatal. Poisoning may occur from absorption through the skin, by inhalation, or by ingestion. Toxic effects are usually delayed for several hours and may include nausea, prostration, burning headache, methaemoglobinaemia with cyanosis, haemolytic anaemia, vomiting (with characteristic odour), convulsions, and coma, ending in death after a few hours.

💊 Treatment of Adverse Effects

Although the benefit of gastric decontamination following ingestion of nitrobenzene is uncertain, gastric lavage or activated charcoal may be considered if given within 1 hour of ingestion. Methaemoglobinaemia may be treated with methylthioninium chloride. Oxygen should be given if cyanosis is severe. If the skin or eyes are splashed with nitrobenzene, contaminated clothing should be removed immediately and the affected areas washed thoroughly with water at room temperature for at least 15 minutes.

💊 Uses

Nitrobenzene is used in the manufacture of aniline, as a preservative in polishes, and in perfumery and soaps.
Published May 08, 2019.