Mastic

(USAN, rINN)

💊 Chemical information

Almáciga; Mastiche; Mastiksi; Mastix; Pistaciju mastika.

Pharmacopoeias.

In Eur..

Ph. Eur. 6.2

(Mastic). The dried resinous exudate obtained from stems and branches of Pistacia lentiscus var. latifolius. It contains a minimum of 1% v/w of essential oil, calculated with reference to the anhydrous drug. It should not be powdered.

💊 Profile

Solutions of mastic in alcohol, chloroform, or ether have been used, applied on cotton wool, as temporary fillings for carious teeth. Compound Mastic Paint (BP 1980) was formerly used as a protective covering for wounds and to hold gauze in position. Mastic gum has been used in the management of peptic ulcer disease.

Peptic ulcer disease.

Mastic may be effective in the treatment of peptic ulcer disease possibly due to an antibacterial action on Helicobacter pylori.1 However, one small clinical study found no benefit.2
1. Huwez FU, et al. Mastic gum kills Helicobacter pylori. N Engl J Med 1998; 339: 1946. Correction. ibid.: 340: 576 [dose]
2. Bebb JR, et al. Mastic gum has no effect on Helicobacter pylori load in vivo. J Antimicrob Chemother 2003; 52: 522–3.

💊 Preparations

Proprietary Preparations

UK: Mastika.
Published May 08, 2019.