Malic Acid

Malic Acid Chemical formula

💊 Chemical information

Acide Malique; Acidum malicum; Acidum Malicum Racemicum; Äppelsyra; Apple Acid; E296; Hydroxysuccinic Acid; Kyselina jablečná racemická; Málico, ácido; Obuoliu ru _ gštis; Omenahappo.
(2RS)-2-Hydroxybutanedioic acid.
Chemical formula: C4H6O5 = 134.1.
CAS — 6915-15-7 (malic acid); 636-61-3 ((+)-malic acid); 97-67-6 (( )-malic acid); 617-48-1 (( )-malic acid).


In Eur.. Also in USNF. Ger. also includes the S-form ((−)-malic acid).

Ph. Eur. 6.2

(Malic Acid). A white or almost white, crystalline powder. Freely soluble in water and in alcohol, sparingly soluble in acetone.


(Malic Acid). A white or practically white, crystalline powder or granules. Very soluble in water; freely soluble in alcohol.

💊 Profile

Malic acid is used in pharmaceutical formulations as an acidifier, flavour, and as an alternative to citric acid in effervescent powders. It is used with butylated hydroxytoluene as an antoxidant in vegetable oils. It is used topically with benzoic acid and salicylic acid for desloughing of ulcers, burns, and wounds, and systemically with arginine in preparations for the treatment of liver disorders. Pastilles containing malic acid are also used in the management of dry mouth.

💊 Preparations

Proprietary Preparations

Multi-ingredient: Austria: Acerbine; Leberinfusion; Rocmaline; Chile: Secand; Fin.: Xerodent; Fr.: Rocmaline; Sphingogel†; Squaphane; SST; Hung.: Rocmalat†; Ital.: Keraflex; Neth.: Sterofundin M; Norw.: Xerodent; S.Afr.: Aserbine; Spain: Acerbiol; Swed.: Xerodent; Switz.: Acerbine†; UK: Aserbine†; Hydrotab; Salivix; SST; USA: Numoisyn; Venez.: Lecivar Plus.
Published May 08, 2019.