Lactobionic Acid

Lactobionic Acid Chemical formula

Chemical information

Acide Lactobionique; Acidum lactobionicum; Kwas laktobionowy; Kyselina laktobionová; Laktobionihappo; Laktobiono ru _ gštis; Laktobionsyra.


In Eur..

Ph. Eur. 6.2

(Lactobionic Acid). A mixture in variable proportions of 4-Oβ-D-galactopyranosyl-D-gluconic acid (C 12 H 22 O 12 = 358.3) and 4-O-β-D-galactopyranosyl-D-glucono-1,5-lactone (C 12 H 20 O 11 = 340.3). A white or almost white powder. Freely soluble in water; slightly soluble in anhydrous ethanol, methyl alcohol, and glacial acetic acid.


Lactobionic acid is used to form water-soluble salts of drugs such as calcium and the macrolide antibacterials clarithromycin and erythromycin. It is present, in the form of potassium lactobionate, in preservation fluids such as UW (University of Wisconsin) solution for organ transplantation; the lactobionate anion acts as an impermeant and provides an osmotic force to oppose cellular oedema in the stored organ. Lactobionic acid has similar properties to gluconic acid and is being tried in skin care products.
Published May 08, 2019.