Kveim Antigen

(rINN)

Chemical information

Antígeno de Kveim.

Profile

Kveim antigen is a fine suspension in physiological saline of sarcoid tissue prepared from spleens taken from patients with active sarcoidosis. It is used as an intradermal injection in the Kveim (Kveim-Siltzbach) test for the diagnosis of sarcoidosis.
1. James DG, Williams WJ. Kveim-Siltzbach test revisited. Sarcoidosis 1991; 8: 6–9.
However, the procedure to identify acceptable sarcoid spleens and the method of preparation were considered sufficient to reduce the risk of transmission of infections2 and of Creutzfeldt-Jakob disease.3
1. Wigly RD. Moratorium on Kveim tests. Lancet 1993; 341: 1284
2. du Bois RM, et al. Moratorium on Kveim tests. Lancet 1993; 342: 173
3. de Silva RN, Will RG. Moratorium on Kveim tests. Lancet 1993; 342: 173.
Published May 08, 2019.