Synonyms: B-cell Stimulatory Factor-2; BSF-2; Hepatocyte-Stimulating Factor; Hybridoma Growth Factor; IFN2 ; IL-6; Interferonβ2.
Cyrillic synonym: Интерлейкин-6.
Interleukin-6 is one of a number of polypeptides known collectively as interleukins. It is produced by many cell types and induces differentiation of B-lymphocytes and activation of T-cells. It has proinflammatory and pyrogenic properties and is involved in the regulation of immune responses and inflammation. Interleukin-6 has also been implicated in haematopoiesis. Atexakin alfa is human recombinant interleukin-6 under investigation. Since overproduction of interleukin-6 plays a crucial role in the pathogenesis of chronic inflammatory diseases, interleukin-6 antibodies and interleukin-6 receptor antagonists are being investigated or used as therapeutic agents.
Published May 08, 2019.