Inositol

(rINN)
Inositol Chemical formula

💊 Chemical information

i-Inositol; meso-Inositol; Inositoli; Inositolum; myo-Inositolum; mio-Inozytol; myo-Inositol; myo-Inositoli; myo-Inositolum. myoInositol.
Chemical formula: C6H12O6 = 180.2.
CAS — 87-89-8.
ATC — A11HA07.
ATC Vet — QA11HA07.

Pharmacopoeias.

In Eur.. Also in USNF.

Ph. Eur. 6.2

(myo-Inositol). A white or almost white, crystalline powder. Very soluble in water; practically insoluble in alcohol.

USNF 26

(Inositol). A white or almost white, crystalline powder. Very soluble in water; practically insoluble in dehydrated alcohol and in ether.

💊 Profile

Inositol, an isomer of glucose, has traditionally been considered to be a vitamin B substance although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. Sources of inositol include whole-grain cereals, fruits, and plants, in which it occurs as the hexaphosphate, fytic acid. It also occurs in both vegetables and meats in other forms. The usual daily intake of inositol from the diet is about 1 g. It is an ingredient of numerous vitamin preparations and dietary supplements, and of preparations promoted for a wide variety of disorders. Inositol appears to be involved physiologically in lipid metabolism and has been tried, with little evidence of efficacy, in disorders associated with fat transport and metabolism. It has been investigated in the treatment of depression and anxiety, in diabetic neuropathy, and in neonatal respiratory distress syndrome and retinopathy of prematurity.

Neonatal respiratory distress syndrome.

Inositol supplementation has been tried in premature infants with respiratory distress syndrome. A meta-analysis1 found that infants given inositol had improved survival and lower rates of bronchopulmonary dysplasia and retinopathy of prematurity than those given placebo.
1. Howlett A, Ohlsson A. Inositol for respiratory distress syndrome in preterm infants. Available in The Cochrane Database of Systematic Reviews; Issu
4. Chichester: John Wiley; 2003 (accessed 19/04/06).

💊 Preparations

Proprietary Preparations

USA: Inositech. Multi-ingredient: Arg.: Bifena; Austral.: Hair and Skin Formula†; LivDetox†; Austria: Aslavital; Lemazol; Braz.: Hecrosine B12†; Hepatogenol†; Hormo Hepatico†; Metiocolin B12; Xantinon Complex; Canad.: Amino-Cerv; Chile: Hepabil; Cz.: Lipovitan†; Fr.: Hepagrume; Ger.: Lipovitan†; Hong Kong: Bilsan; Lipochol; India: Alcrin-M; Delphicol; Indon.: Naturica DFM; Ital.: Digelax†; Hepatos B12; Porfirin 12; Stimolfit; S.Afr.: Hepavite; Prohep; Spain: Complidermol†; Dertrase; Policolinosil; Tri Hachemina; Thai.: Lipochol; Liporon; UK: Lipotropic Factors; USA: Amino-Cerv.
Published May 08, 2019.