Icatibant Acetate

(USAN, rINNM)
Icatibant Acetate Chemical formula
Synonyms: Hoe-140 (icatibant, icatibant acetate); Icatibant, Acétate d’; Icatibanti Acetas; Icatibanto; JE-049 (icatibant). (R)-Arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-thienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isoquinolyl)-carbonyl](2S,3aS,7aS)-[(hexahydro-2-indolinyl)-carbonyl]-(S)-arginine acetate.
Cyrillic synonym: Икатибанта Ацетат.

Chemical information

Chemical formula: C59H89N19O13S,xC2H4O2.
CAS — 130308-48-4 (icatibant); 138614-30-9 (icatibant acetate).

Profile

Icatibant acetate is a selective bradykinin B2 antagonist under investigation for hereditary angioedema.
Published May 08, 2019.