Ibogaine

(BAN, USAN, rINN)
Ibogaine Chemical formula

Chemical information

Ibogaina; NIH-10567. 12-Methoxyibogamine.
Chemical formula: C20H26N2O = 310.4.
CAS — 83-74-9.
NOTE. The following terms have been used as ‘street names’ or slang names for various forms of ibogaine or preparations containing ibogaine: Iboga.

Profile

Ibogaine is a hallucinogenic indole alkaloid extracted from the West African shrub Tabernanthe iboga (Apocynaceae). It has been investigated as an aid to withdrawal from drug addiction.
1. Popik P, et al. 100 years of ibogaine: neurochemical and pharmacological actions of a putative anti-addictive drug. Pharmacol Rev 1995; 47: 235–53
2. Alper KR, et al. Treatment of acute opioid withdrawal with ibogaine. Am J Addict 1999; 8: 234–42
3. Pace CJ, et al. Novel iboga alkaloid congeners block nicotinic receptors and reduce drug self-administration. Eur J Pharmacol 2004; 492: 159–67
4. Hittner JB, et al. Combating substance abuse with ibogaine: preand posttreatment recommendations and an example of successive model fitting analyses. J Psychoactive Drugs 2004; 36: 191–9.
Published May 08, 2019.