Hypoglycin A


Chemical information

Hipoglicina A. L-2-Amino-3-(2-methylenecyclopropyl)propionic acid.
Chemical formula: C7H11NO2 = 141.2.
CAS — 156-56-9.


Hypoglycin A is a toxic substance present in the arillus of unripe ackee (akee), the fruit of Blighia sapida (Sapindaceae). It is responsible for Jamaican vomiting sickness, with symptoms of acute and severe vomiting, hypoglycaemia, muscular weakness, CNS depression, convulsions, and coma, frequently fatal. Glycine has been suggested for the management of hypoglycin A toxicity.
Published May 08, 2019.