Hydroquinine Hydrobromide

(BAN, rINN)
Hydroquinine Hydrobromide Chemical formula

💊 Chemical information

Dihydrochinin Hydrobromide; Dihydroquinine Hydrobromide; Hidroquinina, hidrobromuro de; Hydrochinin Hydrobromide; Methylhydrocupreine Hydrobromide. 8 methoxycinchonan-9-ol hydrobromide.
Chemical formula: C20H26N2O2,HBr = 407.3.
CAS — 522-66-7 (hydroquinine).
ATC — M09AA01.
ATC Vet — QM09AA01.
NOTE. Do not confuse with Hydroquinone.

💊 Profile

Hydroquinine is a derivative of quinine used similarly in the treatment of nocturnal muscle cramps. It is given as the hydrobromide in an oral dose of 200 mg with the evening meal and a further 100 mg at bedtime for 14 days.

Muscle spasm.

Quinine and its derivatives such as hydroquinine have traditionally been used for the prevention of nocturnal cramps but there has been concern over their efficacy and potential for adverse effects, especially in the elderly.
1. Jansen PHP, et al. Randomised controlled trial of hydroquinine in muscle cramps. Lancet 1997; 349: 528–32
2. van Kan HJM, et al. Hydroquinine pharmacokinetics after oral administration in adult patients with muscle cramps. Eur J Clin Pharmacol 2000; 56: 263–7.

💊 Preparations

Proprietary Preparations

Neth.: Inhibin.
Published May 08, 2019.