Hydrastine Hydrochloride

(BAN, rINN)
Hydrastine Hydrochloride Chemical formula

Chemical information

Hidrastina, hidrocloruro de; Hydrastyny chlorowodorek. 6,7Dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5g]isoquinolin-5-yl)isobenzofuran-1(3H)-one hydrochloride.
Chemical formula: C21H21NO6,HCl = 419.9.
CAS — 118-08-1 (hydrastine); 5936-28-7 (hydrastine hydrochloride).

Profile

Hydrastine hydrochloride, the hydrochloride of an alkaloid obtained from Hydrastis canadensis (Ranunculaceae) (see Hydrastis, below), has been reputed to cause uterine contractions and arrest uterine haemorrhage but it is of doubtful value. It was also formerly used in gastrointestinal disorders. Toxic doses are reported to cause strychnine-like convulsions and relaxation of the gut.
Published May 08, 2019.