Grape

(BAN, rINN)

💊 Chemical information

Grapevine; Rebe; Vigne Rouge; Weinstock.

Pharmacopoeias.

Fr. includes Red Vine Extract (Extrait de Vigne Rouge (Sec)), prepared from the leaves.

💊 Profile

The seeds and the leaves of the grape, Vitis vinifera (Vitaceae), are used in herbal medicine. The dried fruit (raisins) have laxative and demulcent properties. Many parts of the plant including the fruit skin, seeds, and leaves are used. Both dietary sources and various extracts are promoted for their antoxidant properties in venous insufficiency and capillary impairment, and it has been suggested that they may protect against atherosclerosis. A standardised red vine leaf extract (AS-195) has been given for the management of chronic venous insufficiency. Grape seed and grape seed extracts have been included in preparations for peripheral vascular disorders and venous insufficiency and for prophylaxis of cardiovascular disorders. Extracts of grape seed proanthocyanidins, including IH636, are being investigated for a range of other disorders in which antoxidant and free-radical scavenging activity is thought to be beneficial, including cancer prevention, hepatic disorders, radiation-induced fibrosis, cataracts, and macular degeneration, although there is currently little evidence of effectiveness. Resveratrol, a compound present in grapes, is also promoted as an antoxidant. Grape seed oil is included in topical preparations. The fresh and dried fruits of the grape and the leaves are used as foodstuffs.
1. Bombardelli E, Morazzoni P. Vitis vinifera L. Fitoterapia 1995; 66: 291–317.

💊 Preparations

Proprietary Preparations

Arg.: Viticalm; Austria: Antistax; Pedopur; Braz.: Celox; Radifree; Vinera; Vitium†; Chile: Endotelon; Juvenit†; Uvanox; Cz.: Antistax; Endotelon†; Fr.: Endotelon; Ger.: Antistax; Hung.: Endotelon; Ital.: Antistax; Pol.: Endotelon; Spain: Antistax; Switz.: Antistax; UK: Antistax. Multi-ingredient: Austral.: Anthogenol; Antioxidant Forte Tablets; Bioglan Pygno-Vite; Bioglan Zellulean with Escin; Lifechange Multi Plus Antioxidant†; Pykno†; Vitanox; Austria: Hepatodoron; Canad.: Glucosamine Joint & Muscle Cream with MSM†; Chile: Celltech Gold; Fr.: A-Flam; D’Contract; Detoxell; Ditavene; Flebior; Jouvence de l’Abbe Soury†; Mediflor Tisane Circulation du Sang No 12; Ophtalmine; Opo-Veinogene; Phlebosedol†; Veinophytum†; Ger.: Hepatodoron; Hong Kong: Proflavanol†; Indon.: Lanaven Plus; Lycoq; Resvica; Ital.: Angiovein; Capill; Mirtilux; Neosulfur; Venalta; Malaysia: Proflavanol; Mex.: Proflavanol; S.Afr.: Hepatodoron; Singapore: Proflavanol; Switz.: Kawaform†; UK: Atopiclair; Xclair; USA: Atopiclair; Pycnogenol Plus.
Published May 08, 2019.