Eucalyptus Oil

(rINNM)

💊 Chemical information

Pharmacopoeias.

In Chin., Eur., and Jpn.

Ph. Eur. 6.2

(Eucalyptus Oil). A colourless or pale yellow liquid with a characteristic aromatic camphoraceous odour and a pungent camphoraceous taste. It is obtained by steam distillation and rectification from the fresh leaves or terminal branches of various species of Eucalyptus rich in cineole. The species mainly used are E. globulus, E. polybractea, and E. smithii. It contains not less than 70% w/w of cineole. Relative density 0.906 to 0.927. Soluble 1 in 5 of alcohol (70%). Store in well-filled airtight containers at a temperature not exceeding 25°. Protect from light.

💊 Adverse Effects and Precautions

The symptoms of poisoning with eucalyptus oil include gastrointestinal symptoms such as epigastric burning, nausea and vomiting, and CNS depression, including coma. Cyanosis, ataxia, miosis, pulmonary damage, delirium, and convulsions may occur. Deaths have been reported. Oily solutions of eucalyptus oil were formerly used in nasal preparations, but this use is now considered unsuitable as the vehicle inhibits ciliary movements and may cause lipoid pneumonia.
1. Patel S, Wiggins J. Eucalyptus oil poisoning. Arch Dis Child 1980; 55: 405
2. Spoerke DG, et al. Eucalyptus oil: 14 cases of exposure. Vet Hum Toxic ol 1989; 31: 166–8
3. Webb NJA, Pitt WR. Eucalyptus oil poisoning in childhood: 41 cases in south-east Queensland. J Paediatr Child Health 1993; 29: 368–71
4. Tibballs J. Clinical effects and management of eucalyptus oil ingestion in infants and young children. Med J Aust 1995; 163: 177–80
5. Anpalahan M, Le Couteur DG. Deliberate self-poisoning with eucalyptus oil in an elderly woman. Aust N Z J Med 1998; 28: 58
6. Darben T, et al. Topical eucalyptus oil poisoning. Australas J Dermatol 1998; 39: 265–7.

💊 Uses and Administration

Eucalyptus oil has been taken orally for catarrh and coughs and is an ingredient of many preparations. It has been used as an inhalation often in combination with other volatile substances. Eucalyptus oil has also been applied as a rubefacient and is used as a flavour. It is also used in aromatherapy.

💊 Preparations

Proprietary Preparations

Austral.: Bosisto’s Eucalyptus Spray; Ger.: Aspecton Eukaps; BronchoTruw Erkaltungsbalsam; Eucotol†; Exeu; Gelodurat†; Pinimenthol Erkaltungsbad fur Kinder; Pinimenthol Erkaltungskapseln†; Pulmotin Inhalat; Schnupfen Kapseln; Tussidermil N; Pol.: Migrenol; Port.: Vicks Vaporub; Switz.: Nicobrevin N†.
Published May 08, 2019.