Coenzyme A

(BANM, USAN, rINNM)

Chemical information

CoA; CoASH; Coenzima A. 5′O-{3-Hydroxy-3-[2-(2-mercaptoethylcarbamoyl)ethylcarbamoyl]-2,2-dimethylpropyl}adenosine-3′-dihydrogenphosphate-5′-trihydrogendiphosphate.
Chemical formula: C21H36N7O16P3S = 767.5.
CAS — 85-61-0.

Profile

Formed from adenosine triphosphate, cysteine, and pantothenic acid, coenzyme A is involved in the body in many physiological roles, including the formation of citrate, the oxidation of pyruvate, the oxidation and synthesis of fatty acids, the synthesis of triglycerides, cholesterol, and phospholipids, and the acetylation of amines, choline, and glucosamine. It has been given by injection in a variety of metabolic disorders.
Published April 28, 2019.