Cobalt Chloride

(BANM, USAN, rINNM)

💊 Chemical information

Cloruro cobaltoso; Cobalto, cloruro de; Cobaltous Chloride; Kobaltu(II) chlorek.
Chemical formula: CoCl2,6H2O = 237.9.
CAS — 7646-79-9 (anhydrous cobalt chloride); 7791-131 (cobalt chloride hexahydrate).

💊 Adverse Effects

Reactions to cobalt have included anorexia, nausea and vomiting, diarrhoea, precordial pain, cardiomyopathy, flushing of the face and extremities, skin rashes, tinnitus, temporary nerve deafness, renal injury, diffuse thyroid enlargement, and hypothyroidism. In large doses it may reduce the production of erythrocytes.
1. Kennedy A, et al. Fatal myocardial disease associated with industrial exposure to cobalt. Lancet 1981; i: 412–4
2. Cugell DW, et al. The respiratory effects of cobalt. Arch Intern Med 1990; 150: 177–83
3. Evans P, et al. Cobalt and cobalt compounds. Toxicity Revie
29. London: HMSO, 1993.

💊 Uses and Administration

Cobalt chloride, when given to both normal and anaemic subjects, produces reticulocytosis and a rise in the erythrocyte count. This property suggested its use in the treatment of certain types of anaemia, but its general therapeutic use is, however, unjustified and not without danger. In veterinary medicine, cobalt chloride has been given as a dietary supplement to ruminants.
Published April 25, 2019.