Cineole

(USAN)
Cineole Chemical formula

💊 Chemical information

Cajuputol; Cineol; Cineolas; Cinéole; Cineolum; Cyneol; Eucaliptol; Eucalyptol thane; 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane.
Chemical formula: C10H18O = 154.2.
CAS — 470-82-6.

Description.

Cineole is a colourless liquid, with an aromatic camphoraceous odour, obtained from eucalyptus oil, cajuput oil, and other oils.

Pharmacopoeias.

In Eur., US, and Viet.

Ph. Eur. 6.2

(Cineole). A clear colourless liquid. It solidifies at about 0.5°. Practically insoluble in water; miscible with alcohol and with dichloromethane. Store in airtight containers. Protect from light.

USP 31

(Eucalyptol). It is obtained from eucalyptus oil and from other sources. Store in airtight containers.

💊 Profile

Cineole has the actions and uses of eucalyptus oil. It has been used in counter-irritant ointments and in dental products. It has also been used in nasal preparations, but oily solutions inhibit ciliary movement and may cause lipoid pneumonia. Preparations containing cineole with other volatile substances have been used in the treatment of renal and biliary calculi.

💊 Preparations

Proprietary Preparations

Cz.: Soledum†; Ger.: Soledum; Soledum Balsam; Ital.: Fluirespir†. Multi-ingredient: Arg.: Aseptobron; Aseptobron Ampicilina†; Aseptobron N; Atomo Desinflamante; Atomo Desinflamante Familiar; Atomo Desinflamante G; Bano Liquido con Eucalipto†; Bronco Etersan; Di-Neumobron; Listerine Clasico; Listerine Cool Mint; Listerine Fresh Burst; NoTos Adultos; Otorinazol†; Refenax Caramelos Expectorantes; Austral.: Bosisto’s Vaporising Ointment; Euky Bearub; Methyl Salicylate Ointment Compound†; Nasex; Spray-Tish Menthol; Tixylix Chest Rub†; Vasylox†; Vicks Sinex; Austria: Rhinospray Plus; Rowachol; Rowatinex; Wick Sinex; Belg.: Balsoclase Expectorans; Eucalyptine; Eucalyptine Le Brun†; Eucalyptine Pholcodine; Eucalyptine Pholcodine Le Brun†; Inhalene†; Inhalo Rhinathiol; Inopectol; Olbas; Pulmex; Pulmex Baby; Braz.: Algice; Angino-Rub; BaldinCE†; Bromil; Broncopinol†; Canfomenol†; Eucaliptan†; Fluomint; Gargotan†; Gripanil†; Gripomatine†; Griponia†; Gripsay; Inhadrina†; Inhalante Yatropan; Killgrip†; Mentalol†; Ozonyl; Ozonyl Aquoso; Ozonyl Expectorante; Pastilhas Valda; Pectal†; Penetro; Quelodin†; Tabletes Valda†; Tetrapulmo; Transpulmin; Transpulmin Balsamo; Transpulmin†; Tripulmin Balsamico†; Tripulmin†; Valda†; Vick Pastilhas; Canad.: Alsirub†; Antiseptic Mouthwash; Arthriflex; Cal Mo Dol; Carboseptol†; Demo-Cineol; Listerine; Listerine Antiseptic Tartar Control; Mielocol; Mouthwash Antiseptic & Gargle†; Physio-Rub; Thermo Rub; Valda; Chile: Listerine; Oralfresh Citrus; Oralfresh Clasico; Rowatinex; Cz.: Biocalyptol S†; Rowachol; Rowatinex; Denm.: Otrivin Menthol; Fin.: Otrivin Menthol; Fr.: Biolau; Dinacode avec codeine†; Dinacode†; Essence Algerienne; Eucalyptine; Eucalyptine Le Brun; Hexapneumine; Listerine; Listerine protection dents et gencives; Neo-Codion†; Pectoderme†; Pholcones Bismuth; Pulmofluide Simple; Valda; Vegebom; Ger.: Eufimenth-Balsam N†; Rhinospray Plus; Rhinospray sensitiv; Rowachol; Rowachol comp†; Rowachol-Digestiv; Rowatinex; Transpulmin Balsam; Gr.: Cedovix; Faragel-Forte; Hong Kong: Biocalyptol†; Cool Mint Listerine; Listerine; Listerine Tartar Control; Listerine Teeth and Gum Defence; Neo-Rowachol; Neo-Rowatinex; Rowachol; Rowatinex; Valda†; Hung.: Rhinospray Plus; Rowachol; Rowatinex; India: Dristan Nasal Drops; Endrine; Endrine Mild; Karvol Plus; Sinarest Vapocaps; Indon.: Dactylen; Listerine; Listerine Coolmint; Irl.: Rowachol; Rowatinex; Valda†; Israel: Gargol; Rowachol; Rowatinex; Ital.: Abiostil; Balsamico; Balta Intimo†; Calyptol; Lipobalsamo; Listerine Fresh Citrus; Listerine Tartar Control; Paidorinovit; Pastiglie Valda†; Pulmarin; Pumilene Vapo; Rinogutt Eucalipto-Fher; Rinovit; Transpulmina Gola; Transpulmina Tosse; Vicks Baby Balsam†; Vicks Sinex; Malaysia: Listerine†; Purporent†; Rowachol; Rowatinex; Mex.: Andociclina Balsamica†; Bronkitose Mielimon; Cholex; Eucalin†; Guayalin; GuayalinPlus†; Iodex Cristal; Listerine; Numonyl†; Neth.: Balsoclase Compositum; Balsoclase-E; Otrivin Menthol; Rhinospray met menthol; NZ: Listerine; Listerine Tartar Control; Tixylix Chest Rub; Vicks Sinex; Philipp.: Kamillosan M; Listerine Coolmint; Listerine Fresh Citrus; Listerine Freshburst; Listerine Original; Listerine Tartar Control; Listerine Teeth & Gum Defense; Rhea Superscent Oil; Rowachol; Rowatinex; Transpulmin Balsam; Pol.: Rowachol; Rowatinex; Salviasept; Terpichol; Port.: Listerine†; Rectopulmo Adultos†; Rectopulmo Infantil†; Transpulmina; Valda†; Rus.: Nazol Advance (Назол Адванс); S.Afr.: Respisniffers; Woodwards Inhalant; Singapore: Listerine; Listerine Cool Mint; Listerine Fresh Burst; Listerine Tartar Control; Spain: Balsamo Kneipp†; Broncovital†; Brota Rectal Balsamico; Caltoson Balsamico; Caramelos Agua del Carmen†; Diminex Antitusigeno; Doctomitil†; Dolmitin; Eucalyptospirine†; Eupnol; Mentobox; Pastillas Juanola†; Pastillas Pectoral Kely; Piorlis; Pulmofasa; Retarpen Balsamico†; Rinobanedif; Rowachol; Rowanefrin; Sinus Inhalaciones; Tifell†; Trophires†; Vitavox Pastillas†; Swed.: Otrivin Menthol; Switz.: Nasobol N; Neo-Bronchol; Onguent aux herbes Keller; Rectoseptal-Neo bismuthe; Rectoseptal-Neo simple; Resorbane; Rowachol; Sedasept†; Sedotussin†; Transpulmin N; Vicks Sinex; Thai.: Dexalin; Hot Ize; Olympic Balm†; Rowachol; Rowatinex; Sore Mouth Gel; Turk.: Bugumentol; Bugusan; Buguseptil; Gelocaps; Mentimol; Mentolin; Mentoseptol; Otaci Oka Mentol; Otaci Salvia; Rinolar; Sulfarhin; UK: Dubam; Listerine Antiseptic Mouthwash; Lockets; Nostroline; Nowax; Rowachol; USA: Babee; BFI; Listerine; Pfeiffer’s Cold Sore; Rid-aPain; Saratoga; Sting-Eze; Venez.: Derpinol†; Robitussin Caramelos†; Rowachol; Rowatinex; Transmin.
Published April 02, 2019.