Chrysoidine Hydrochloride Citrate


Chemical information

Crisoidina, hidrocloruro del citrato de. 4-Phenylazobenzene-1,3diamine hydrochloride citrate; Azobenzene-2,4-diamine hydrochloride citrate.
Chemical formula: C12H12N4,HCl,C6H8O7 = 440.8.


Chrysoidine hydrochloride citrate has been used as a dye but has been associated with tumours of the bladder.


The development of tumours of the urinary bladder in anglers was possibly associated with the use of chrysoidine hydrochloride (chrysoidine Y; CI Basic Orange 2; Colour Index No. 11270) for colouring the maggots used as bait.1-3
1. Searle CE, Teale J. Chrysoidine-dyed bait: a possible carcinogenic hazard to anglers? Lancet 1982; i: 564
2. Sole GM. Maggots dyed with chrysoidine: a possible risk to anglers. BMJ 1984; 289: 1043–4
3. Massey JA, et al. Maggots dyed with chrysoidine. BMJ 1984; 289: 1451–2.
Published March 21, 2019.