Chrysoidine Hydrochloride Citrate

(rINNM)

Chemical information

Crisoidina, hidrocloruro del citrato de. 4-Phenylazobenzene-1,3diamine hydrochloride citrate; Azobenzene-2,4-diamine hydrochloride citrate.
Chemical formula: C12H12N4,HCl,C6H8O7 = 440.8.

Profile

Chrysoidine hydrochloride citrate has been used as a dye but has been associated with tumours of the bladder.

Carcinogenicity.

The development of tumours of the urinary bladder in anglers was possibly associated with the use of chrysoidine hydrochloride (chrysoidine Y; CI Basic Orange 2; Colour Index No. 11270) for colouring the maggots used as bait.1-3
1. Searle CE, Teale J. Chrysoidine-dyed bait: a possible carcinogenic hazard to anglers? Lancet 1982; i: 564
2. Sole GM. Maggots dyed with chrysoidine: a possible risk to anglers. BMJ 1984; 289: 1043–4
3. Massey JA, et al. Maggots dyed with chrysoidine. BMJ 1984; 289: 1451–2.
Published March 21, 2019.