Catalase

(rINN)

💊 Chemical information

Caperase; Catalasa; Equilase; Optidase.

💊 Profile

Catalase is an enzyme obtained from a wide variety of biological sources including animal liver (hepatocatalase) and certain bacteria and fungi. It is a protein composed of 4 polypeptide subunits, the precise composition of which varies according to the source, and has a molecular weight of about 240 000. Catalase has the ability to promote the decomposition of hydrogen peroxide to water and oxygen. It has been applied to wounds and skin ulcers and has also been used in the treatment of eczema. It has sometimes been used with glucose oxidase in food preservation to break down hydrogen peroxide produced during oxidation of glucose, and is also included in preparations for contact lens care to neutralise hydrogen peroxide. Catalase is a free-radical scavenger and has been investigated for its ability to limit reperfusion injury thought to be related to freeradical production. Combinations of catalase with superoxide dismutase have also been investigated.
1. Greenwald RA. Superoxide dismutase and catalase as therapeutic agents for human diseases: a critical review. Free Radic Biol Med 1990; 8: 201–9.

💊 Preparations

Proprietary Preparations

Ital.: Citrizan; Spain: Biocatalase†. Multi-ingredient: Arg.: One Step†; Oxysept Comfort; Vitix; Canad.: UltraCare; Fr.: Pulvo 47 Neomycine†; Pulvo 47†; Ger.: Pulvo; Pulvo Neomycin; Gr.: Pulvo 47; Ital.: Citrizan Antibiotico; NZ: Omnicare 1 Step; Thai.: Pulvo 47; Turk.: Pulvo 47; USA: UltraCare.
Published February 14, 2019.