Berberine Chemical formula

💊 Chemical information

Berberina. 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6a]quinolizinium.
Chemical formula: C20H18NO4 = 336.4.
CAS — 2086-83-1 (berberine); 633-65-8 (berberine chloride); 633-66-9 (berberine sulfate).


Chin. includes berberine chloride. Jpn includes berberine chloride hydrate and berberine tannate. Viet. includes berberine chloride dihydrate.

💊 Profile

Berberine is a quaternary alkaloid present in hydrastis, in various species of Berberis, and in many other plants. It has been used as a bitter and as a flavour in food and alcoholic drinks. It possesses antimicrobial activity and has also been tried as various salts in a number of infections.
1. Khin-Maung-U, et al. Clinical trial of berberine in acute watery diarrhoea. BMJ 1985; 291: 1601–5
2. Rabbani GH, et al. Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae. J Infect Dis 1987; 155: 979–84
3. Vennerstrom JL, et al. Berberine derivatives as antileishmanial drugs. Antimicrob Agents Chemother 1990; 34: 918–21
4. Phillipson JD, Wright CW. Medicinal plants in tropical medicine: 1 Medicinal plants against protozoal diseases. Trans R Soc Trop Med Hyg 1991; 85: 18–21.

💊 Preparations

Proprietary Preparations

Austral.: Murine; Venez.: Irisol†. Multi-ingredient: Braz.: Neo Quimica Colirio; Visazul; Visolon; Fr.: Sedacollyre; India: Emantid†.
Published January 13, 2019.