Arachis Oil


💊 Chemical information

Arachide, huile d’, raffinée; Arachidis Oleum; Arachidis oleum raffinatum; Cacahuete, aceite de; Earth-nut Oil; Erdnussöl; Finomított földimogyoróolaj; Ground-nut Oil; Huile d’Arachide; Jordnötolja, raffinerad; Maapähkinäöljy, puhdistettu; Nut Oil; Ol.
Arach.; Olej arachidowy oczyszczony; Óleo de Amendoim; Oleum Arachis; Peanut Oil; Podzemnicový olej čištěný; Refined Arachis Oil; Yerfıstığı Yağı; Žeme˙sriešutu aliejus.


In Eur., Int., and Jpn. Also in USNF. Eur. also includes hydrogenated arachis oil.

Ph. Eur. 6.2 (Arachis Oil, Refined; Arachis Oil BP 2008). The refined fatty oil obtained from the shelled seeds of Arachis hypogaea. A suitable antoxidant may be added. It is a clear, yellowish viscous liquid consisting of glycerides, chiefly of oleic and linoleic acids, with smaller amounts of other acids. It solidifies at about 2°. Very slightly soluble in alcohol; miscible with petroleum spirit. Store in well-filled containers. Protect from light. The BP 2008 gives Ground-nut Oil and Peanut Oil as approved synonyms.

Ph. Eur. 6.2 (Arachis Oil, Hydrogenated; Arachidis Oleum Hydrogenatum). Arachis oil that has been refined, bleached, hydrogenated, and deodorised. It is a white or faintly yellowish soft mass that melts to a clear pale yellow liquid when heated. Practically insoluble in water; very slightly soluble in alcohol; freely soluble in dichloromethane and in petroleum spirit (b.p. 65° to 70°). Protect from light.


(Peanut Oil). The fully-refined (alkali-refined, bleached, and deodorised at 230° to 260°) oil obtained from the seed kernels of one or more of the cultivated varieties of Arachis hypogaea (Leguminosae). It is a colourless or pale yellow, oily liquid with a bland taste; it may have a characteristic nutty odour. Very slightly soluble in alcohol; miscible with carbon disulfide, with chloroform, and with ether. Store at a temperature not exceeding 40° in airtight containers. Protect from light.

💊 Profile

Emulsions containing arachis oil are used in nutrition. Arachis oil is given as an enema for softening impacted faeces. It is used in drops for softening ear wax and in emollient creams. Arachis oil is given by mouth, usually with sorbitol, as a gallbladder evacuant prior to cholecystography.


It has been suggested that the use during infancy of preparations containing arachis oil, including infant formulae and topical preparations, may be responsible for sensitisation to peanut, with a subsequent risk of hypersensitivity reactions.1-3The arachis oil used in such preparations is refined oil and it has been pointed out that such oil should not contain the proteins that produce allergic reactions in susceptible people.4,5 In the USA, heating of arachis oil during preparation, to further reduce protein content, has been proposed.6 Nonetheless, some consider that sufficient protein may be present in refined oil to cause sensitisation.7 However, others have pointed out that to date, there are no reliable data about doses of topical arachis oil needed to induce sensitisation via the epidermal route and that the benefit of protecting skin barrier functions in atopic patients with products using refined arachis oil outweigh possible risks of sensitisation.8 In the UK, the CSM considered that there was not enough evidence to conclude that medicinal products containing arachis oil could lead to sensitisation.9 However, although they considered the risk of a reaction to be low, they recommended that patients known to be allergic to peanuts should not use medicines containing arachis oil (nor, because of the possibility of cross-sensitivity, should patients allergic to soya), and that such medicines should include an appropriate warning in the labelling.
1. de Montis G, et al. Sensitisation to peanut and vitamin D oily preparations. Lancet 1993; 341: 1411
2. Lever LR. Peanut and nut allergy: creams and ointments containing peanut oil may lead to sensitisation. BMJ 1996; 313: 299
3. Lack G, et al. Factors associated with the development of peanut allergy in childhood. N Engl J Med 2003; 348: 977–85
4. Hourihane J O’B, et al. Randomised, double blind, crossover challenge study of allergenicity of peanut oil in subjects allergic to peanuts. BMJ 1997; 314: 1084–8
5. Committee on Toxicity of chemicals in Food, Consumer Products and the Environment. Peanut allergy. London: Department of Health, 1998
6. Wilkin JK, et al. Peanut allergy. N Engl J Med 2003; 349: 302
7. Lack G, et al. Peanut allergy. N Engl J Med 2003; 349: 302–3
8. Ring J, Möhrenschlager M. Allergy to peanut oil — clinically relevant? J Eur Acad Dermatol Venereol 2007; 21: 452–5
9. Committee on Safety of Medicines/Medicines and Healthcare Regulatory Agency. Medicines containing peanut (arachis) oil. Current Problems 2003; 29: 5. Also available at: http:// dDocName=CON007450&RevisionSelectionMethod= LatestReleased (accessed 14/07/06)

💊 Preparations

BP 2008: Arachis Oil Enema.

Proprietary Preparations

Austral.: Calogen; Chile: Oilatum; Denm.: Olie; Fin.: Calogen; Ger.: Olbad Cordes F; Indon.: Oilatum Cream; Irl.: Calogen; Fletcher’s Arachis Oil; Oilatum Cream; Ital.: Calogen; Mex.: Dermo Bell; Nutrisil; Oilatum; NZ: Calogen; S.Afr.: Oilatum Cream; Singapore: Oilatum Cream; UK: Calogen; Fletchers Arachis Oil Retention Enema†. Multi-ingredient: Austral.: Cerumol; Gold Cross Skin Basics Zinc Cream†; Medevac†; Austria: Balneum F; Chile: Tar y t a r†; Cz.: Balneum Hermal F; Ger.: Balneum F; Parfenac Basisbad†; Irl.: Cerumol; Hydromol†; Israel: Balneum F; Cerumol; Ital.: Balneum Hermal Forte; NZ: Medevac†; Pol.: Balneum Hermal F; S.Afr.: Cerumol; Haarlemensis; Singapore: Cerumol; Spain: Emolytar; Switz.: Balmed Hermal F; Balneum Hermal F†; UK: Cerumol; Earex; Hewletts; Nowax; Red Oil; Soothol.
Published December 25, 2018.