Cholesterol

(BAN, USAN, rINN)
Cholesterol Chemical formula
Synonyms: Cholesterin; Cholestérol; Cholesterolis; Cholesterolum; Colesterina; Colesterol; Kolesterol; Kolesteroli; Koleszterin; Koleszterin. Cholest-5-en-3
Cyrillic synonym: Холестерин; Холестерол.

💊 Chemical information

Chemical formula: C27H46O = 386.7.
CAS — 57-88-5.

Pharmacopoeias.

In Eur. and Jpn. Also in USNF.

Ph. Eur. 6.2

(Cholesterol). A white or almost white, crystalline powder. It is sensitive to light. M.p. 147° to 150°. Practically insoluble in water; sparingly soluble in alcohol and in acetone. Protect from light.

USNF 26

(Cholesterol). White or faintly yellow, practically odourless, pearly leaflets, needles, powder, or granules. It acquires a yellow to pale tan colour on prolonged exposure to light. M.p. 147° to 150°. Insoluble in water; slowly soluble 1 in 100 of alcohol; soluble 1 in 50 of dehydrated alcohol; soluble in acetone, in chloroform, in dioxan, in ether, in ethyl acetate, in petroleum spirit, and in vegetable oils. Protect from light.

💊 Profile

Cholesterol imparts water-absorbing power to pharmaceutical preparations and is used as an emulsifying agent. It has emollient activity and is used mainly in topical preparations. It is also used in ophthalmic and vaginal formulations, and in preparations for parenteral use. Cholesteryl benzoate has been used as an ingredient in dermatological preparations.

💊 Preparations

Proprietary Preparations

Fr.: Senophile†. Multi-ingredient: Arg.: Liposomas; Belg.: Senophile; Chile: Perfungol.
Published October 21, 2018.