Methyl Ethyl Ketone

(BAN, USAN, rINN)
Methyl Ethyl Ketone Chemical formula
Synonyms: Ethyl Methyl Ketone; Etylometyloketon; MEK; Metiletilcetona; Metyloetyloketon. Butan-2-one.
Cyrillic synonym: Метилэтилкетон.

💊 Chemical information

Chemical formula: C4H8O = 72.11.
CAS — 78-93-3.

Description.

Methyl ethyl ketone is a colourless flammable liquid with an acetone-like odour. Wt per mL about 0.81 g. B.p. 79° to 81°. Soluble in water; miscible with alcohol and with ether. Store in airtight containers.

💊 Adverse Effects

Methyl ethyl ketone is irritant. Inhalation may result in mild CNS effects including headache and dizziness; nausea and vomiting may also occur. n-Hexane/Methyl Ethyl Ketone 2025 Methyl ethyl ketone may be implicated in volatile substance abuse.
1. WHO. Methyl ethyl ketone. Environmental Health Criteria 143. Geneva: WHO, 1992. Available at: http://www.inchem.org/ documents/ehc/ehc/ehc143.htm (accessed 30/06/04)

Effects on the nervous system.

There are isolated reports of neurotoxicity produced by methyl ethyl ketone alone.1 These include 1 of retrobulbar neuritis and 1 of peripheral neuropathy. It has been suggested, however, that methyl ethyl ketone potentiates the peripheral neuropathy induced by methyl butyl ketone and n-hexane. For further discussion of neurotoxicity after occupational exposure to solvents including methyl ethyl ketone, see under Toluene.
1. Lolin Y. Chronic neurological toxicity associated with exposure to volatile substances. Hum Toxicol 1989; 8: 293–300.

💊 Uses

Methyl ethyl ketone is used as an industrial solvent and as an extraction solvent in food processing.
Published November 21, 2018.