Epichlorohydrin

(BAN, USAN, rINN)
Epichlorohydrin Chemical formula
Synonyms: Epiclorhidrina. 1-Chloro-2,3-epoxypropane.
Cyrillic synonym: Эпихлоргидрин.

💊 Chemical information

Chemical formula: C3H5ClO = 92.52.
CAS — 106-89-8.

Description.

Epichlorohydrin is a colourless, flammable liquid. Wt per mL about 1.18 g. B.p. 115° to 118°. Store in airtight containers.

Stability.

The vapour of epichlorohydrin forms explosive mixtures with air. Harmful gases including phosgene are liberated on heating of epichlorohydrin.

💊 Adverse Effects and Precautions

Epichlorohydrin is irritant. It has been shown to be carcinogenic in animals.
1. WHO. Epichlorohydrin. Environmental Health Criteri
33. Geneva: WHO, 1984. Available at: http://www.inchem.org/ documents/ehc/ehc/ehc33.htm (accessed 30/06/04
2. WHO. Epichlorohydrin health and safety guide. IPCS Health and Safety Guid
8. Geneva: WHO, 1987. Available at: http:// www.inchem.org/documents/hsg/hsg/hsg008.htm (accessed 30/06/04
3. Health and Safety Executive. Ammonia, 1-chloro-2,3-epoxypropane (epichlorohydrin), carcinogenicity of cadmium and its compounds. Toxicity Revie
24. London: HMSO, 1991
4. Kolman A, et al. Genotoxic effects of ethylene oxide, propylene oxide and epichlorohydrin in humans: update review (1990–2001). Mutat Res 2002; 512: 173–94.

Handling.

Suitable precautions should be taken to avoid skin contact with epichlorohydrin as it can penetrate skin and produce systemic toxicity.

💊 Uses

Epichlorohydrin is used as an industrial solvent.
Published November 02, 2018.