Meteneprost

(USAN, rINN)
Synonyms: 9-Deoxo-16,16-dimethyl-9-methylene-prostaglandin E 2 ; Méténéprost; Meteneprostum; U-46785. (5Z,13E)-(8R,11R,12R,15R)11,15-Dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dienoic acid; (Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(3R)-3-hydroxy4,4-dimethyloct-1-enyl]-5-methylenecyclopentyl}hept-5-enoic acid.
Cyrillic synonym: Метенепрост.

Chemical information

Chemical formula: C23H38O4 = 378.5.
CAS — 61263-35-2.

Profile

Meteneprost is a synthetic derivative of dinoprostone. It is a uterine stimulant and has been studied for the termination of pregnancy.
1. Takkar D, et al. Early abortion by mifepristone (RU 486) followed by vaginal gel (meteneprost) versus oral (misoprostol) prostaglandin. Adv Contracept 1999; 15: 163–73
2. An ICMR Task Force Study. A multicentre randomized comparative clinical trial of 200 mg RU486 (mifepristone) single dose followed by either 5 mg 9-methylene PGE gel (meteneprost) or 600 μg oral PGE (misoprostol) for termination of early pregnancy within 28 days of missed menstrual period. Contraception 2000; 62: 125–30.
Published November 02, 2018.