Ferrous Gluconate

(rINN)
Ferrous Gluconate Chemical formula

💊 Chemical information

E579; Eisen(II)-Gluconat; Ferroglukonaatti; Ferroglukonat; Ferrosi gluconas; Ferrosi Gluconas Hydricus; Ferroso, gluconato; Geležies(II) gliukonatas; Gluconate ferreux; Glukonan železnatý hydrát; Vas(II)-glükonát; Z elaza(II) glukonian. Iron (II) di( nate).
Chemical formula: C12H22FeO14,xH2O.
CAS — 299-29-6 (anhydrous ferrous gluconate); 1238915-0 (ferrous gluconate dihydrate).
ATC — B03AA03.
ATC Vet — QB03AA03.

Pharmacopoeias.

In Eur.. Chin. and US specify the dihydrate.

Ph. Eur. 6.2

(Ferrous Gluconate). A greenish-yellow to grey powder or granules. It contains not less than 11.8% and not more than 12.5% of ferrous iron calculated with reference to the dried substance. Freely but slowly soluble in water producing a greenish-brown solution, more readily soluble in hot water; practically insoluble in alcohol. A 10% solution in water has a pH of 4.0 to 5.5 three to four hours after preparation. Protect from light.

USP 31

(Ferrous Gluconate). A yellowish-grey or pale greenish-yellow, fine powder or granules having a slight odour resembling that of burnt sugar. Soluble 1 in 5 of water; practically insoluble in alcohol. A 5% solution in water is acid to litmus. Store in airtight containers.

💊 Profile

Ferrous gluconate is used as a source of iron for iron-deficiency anaemia. It is given orally in doses of up to 1.8 g daily (equivalent to up to 210 mg of iron daily).

💊 Preparations

BP 2008: Ferrous Gluconate Tablets; USP 31: Ferrous Gluconate Capsules; Ferrous Gluconate Elixir; Ferrous Gluconate Tablets.

Proprietary Preparations

Austral.: Fergon†; Austria: Losferron; Belg.: Losferron; Canad.: NovoFerrogluc; Chile: Glucoferro K; Cz.: Losferron; Ger.: Eisen-Sandoz; Ferrum Verla; Losferron; Rulofer G; Vitaferro; Israel: Ferro; Ferro-Nes; Ital.: Auxofer; Bioferal; Bioglufer; Blizer; Blustark; Crom; Cromatonferro; Effegyn; Emonorm†; Emoxiron; Eriglobin; Eritropiu; Ferig; Ferro Complex; Ferrogyn; Flexifer†; Gloros; Glucoferro; Losferron; Megafer; Monoferro; Prontoferro; Sidervim; Sustemial; Neth.: Losferron; NZ: Fergon†; Pol.: Ascofer; Port.: Anemital†; Bioferro; Hemototal; Losferron†; Rus.: Ferronal (Ферронал); Spain: Ferrum Sandoz; Losferron; Switz.: Loesfer†; Lufer; Turk.: Losferron; USA: Fergon; Venez.: Ferroper†; Irolen†; Salfer; Yisafer. Multi-ingredient: Austria: Losferron-Fol; Fr.: Tot’Hema; Ger.: Biovital Aktiv†; Ferro-C-Calcium; Ferrodix†; Floradix Krauterblut; India: Elferri†; Gynae-CVP; JP Tone; Livogen Hemtonic; Pentavite†; Indon.: Adfer; Biosanbe; Diabion; Emibion; Habebion; Inbion; Maltiron; Muveron; Neogobion; Opibion; Sangobion; Sangofer; Sangovitin; Tropifer; Vitabion; Malaysia: Sangobion; Philipp.: Sangobion; Pol.: Additiva Ferrum; Port.: Tot’Hema; Rus.: Tot’Hema (Тотема); S.Afr.: Kiddie Vite†; Singapore: Neogobion; Sangobion; Spain: Clamarvit†; Switz.: Duofer; Duofer Fol; Ferrascorbin; Thai.: Ferro-Be-Sian; Glufer-C; Turk. : Ferro-Vital; UK: Foresight Iron Formula; USA: Compete; Ferralet Plus†; Hytinic†; Iromin-G; Mission Surgical Supplement†; Venez.: Gestocal†.
Published December 15, 2018.