Vapreotide

(BAN, USAN, rINN)
Vapreotide Chemical formula
Synonyms: BMY-41606; RC-160; Vapreotida; Vapréotide; Vapreotidum. DPhenylalanylcysteinyl
Cyrillic synonym: Вапреотид.

Chemical information

Chemical formula: C57H70N12O9S2 = 1131.4.
CAS — 103222-11-3.
ATC — H01CB04.
ATC Vet — QH01CB04.

Profile

Vapreotide is a somatostatin analogue similar to octreotide (p.1803). It is under investigation in the management of various disorders, including bleeding oesophageal varices, gastrointestinal and pancreatic fistulas, acromegaly, carcinoid tumours, and for the prevention of postoperative complications following pancreatic surgery.
1. Eriksson B, et al. The use of new somatostatin analogues, lanreotide and octastatin, in neuroendocrine gastro-intestinal tumours. Digestion 1996; 57 (suppl 1): 77–80
2. Calès P, et al. Early administration of vapreotide for variceal bleeding in patients with cirrhosis. N Engl J Med 2001; 344: 23–8
3. Anonymous. Vapreotide: BMY 41606, RC 160, Sanvar. Drugs R D 2003; 4: 326–30.
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Published October 07, 2018.