Sodium Sulfate

Synonyms: E514; Glauber’s Salt; Natrii sulfas decahydricus; Natrii Sulphas; Natrio sulfatas dekahidratas; Natrium Sulfuricum Crystallisatum; Natriumsulfaattidekahydraatti; Natriumsulfatdekahydrat; Nátrium-szulfát-dekahidrát; Síran sodný dekahydrát; Sodium (sulfate de) décahydraté; Sodium Sulphate; Sodium Sulphate Decahydrate; Sodu siarczan dziesięciowodny; Sulfato de sodio.
Cyrillic synonym: Глауберова соль; Сульфат Натрия.

💊 Chemical information

Chemical formula: Na2SO4,10H2O = 322.2.
CAS — 7727-73-3 (sodium sulfate decahydrate).
ATC — A06AD13; A12CA02.
ATC Vet — QA06AD13; QA12CA02.


In Chin., Eur., Int., and Viet. US includes a single monograph for both the anhydrous form and the decahydrate.

Ph. Eur. 6.2

(Sodium Sulphate Decahydrate; Sodium Sulphate BP 2008). A white or almost white, crystalline powder or colourless, transparent crystals. Freely soluble in water; practically insoluble in alcohol. It partly dissolves in its own water of crystallisation at about 33°. It loses between 52.0 and 57.0% of its weight on drying.

USP 31

(Sodium Sulfate). It contains 10 molecules of water of hydration or is anhydrous. The decahydrate loses between 51 and 57% of its weight on drying and the anhydrous form loses not more than 0.5% of its weight. Large, colourless, odourless, transparent crystals or a granular powder. It effloresces rapidly in air, liquefies in its water of hydration at about 33°, and loses all of its water of hydration at about 100°. Freely soluble in water; insoluble in alcohol; soluble in glycerol. Store in airtight containers, preferably at a temperature not exceeding 30°.

💊 Profile

Sodium sulfate has been used as an osmotic laxative. It is also given in dilute solution (about 0.5%) with a high molecular weight macrogol for prompt bowel evacuation before investigational procedures or surgery. Sodium sulfate is also used as an additive in foods. For the general properties of sodium salts.

💊 Preparations

USP 31: Sodium Sulfate Injection.

Proprietary Preparations

Austral.: Celloids SS 69. Multi-ingredient: Arg.: Magnesia Phosphorica I Oligoplex; Austral.: Duo Celloids SPSS; Duo Celloids SSMP; Duo Celloids SSPC; Duo Celloids SSS; Iron Compound†; Liv-Detox†; Silybum Complex†; Canad.: Normo Gastryl; Fr.: Actisoufre; Digedryl; Hepargitol; Normogastryl†; Oxyboldine; Prefagyl†; Ital.: Argirofedrina†; Pol.: Sal Ems Artificiale; Sal Ems Factitium; Sal Vichy Factitium; Spain: Darmen Salt; Digestovital†; Leberetic; Lebersal; Salcedol; Switz.: Padma-Lax; Padmed Laxan; Thai.: Ulgastrin; USA: Tr iv; Venez.: Topdent†.
Published April 02, 2019.