Casanthranol

(USAN)
Casanthranol Chemical formula
Synonyms: Casantranol.
Cyrillic synonym: Казантранол.

💊 Chemical information

CAS — 8024-48-4.

Pharmacopoeias.

In US.

USP 31

(Casanthranol). It is obtained from cascara. It contains not less than 20% of total hydroxyanthracene derivatives calculated on the dried basis, of which not less than 80% consists of cascarosides, both calculated as cascaroside A (C 27 H 32 O 14 = 580.5). It is a light tan to brown, amorphous, hygroscopic powder. Freely soluble in water with some residue; partially soluble in methyl alcohol and in hot isopropyl alcohol; practically insoluble in acetone. Store in airtight containers at a temperature not exceeding 30°. Protect from light.

💊 Profile

Casanthranol is an anthraquinone stimulant laxative with general properties similar to those of senna. It is given in usual oral doses of 30 to 60 mg daily with a faecal softener. In severe cases a dose of 90 mg daily, or 60 mg twice daily, may be given.

💊 Preparations

Proprietary Preparations

Belg.: Cascalax†; Neth.: Cascalax. Multi-ingredient: Arg.: Bil 13; En-Ga-Lax; Canad.: Peri-Colace†; Spain: Laxvital; USA: Black-Draught†; Docusoft Plus; Genasoft Plus Softgels†; Laxative & Stool Softener; Peri-Dos Softgels†; Silace-C†.
Published December 11, 2018.