Trafermin

(USAN, rINN)
Synonyms: CAB-2001; Trafermina; Trafermine; Traferminum. 2-155-Basic fibroblast growth factor (human clone duced).
Cyrillic synonym: Трафермин.

💊 Chemical information

CAS — 131094-16-1.

💊 Profile

Trafermin is a human recombinant basic fibroblast growth factor (b-FGF) that promotes tissue granulation and the formation of new blood vessels. It is used as a topical liquid spray for the treatment of burns and intractable skin ulcers.
1. Robson MC, et al. Sequential cytokine therapy for pressure ulcers: clinical and mechanistic response. Ann Surg 2000; 231: 600–11
2. Payne WG, et al. Long-term outcome study of growth factortreated pressure ulcers. Am J Surg 2001; 181: 81–6
3. Ichioka S, et al. The positive experience of using a growth factor product on deep wounds with exposed bone. J Wound Care 2005; 14: 105–9
4. Motomura H, et al. Aggressive conservative therapy for refractory ulcer with diabetes and/or arteriosclerosis. J Dermatol 2006; 33: 353–9.

💊 Preparations

Proprietary Preparations

Jpn: Fiblast.
Published January 23, 2019.