Avobenzone

(USAN, rINN)
Avobenzone Chemical formula
Synonyms: Avobenzona; Avobenzonum; Butylmethoxydibenzoylmethane; 4tert-Butyl-4′-methoxydibenzoylmethane. 1-(ptert-Butylphenyl)-3-(p-methoxyphenyl)-1,3-propanedione; 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione.
Cyrillic synonym: Авобензон.

Chemical information

Chemical formula: C20H22O3 = 310.4.
CAS — 70356-09-1.

Pharmacopoeias.

In US.

USP 31

(Avobenzone). M.p. 81° to 86°. Store in airtight containers. Protect from light.

Profile

Avobenzone is a substituted dibenzoylmethane used by topical application as a sunscreen. Dibenzoylmethanes absorb light in the UVA range and may therefore be used with other sunscreens that absorb UVB light to prevent sunburn; they will also provide some protection against drug-related or other photosensitivity reactions associated with UVA light. Contact and photocontact allergic dermatitis has occasionally been reported with the topical use of dibenzoylmethane sunscreens.
Published November 04, 2018.