Asoxime Chloride

(BAN, USAN, rINN)
Asoxime Chloride Chemical formula

Chemical information

Asoxima, cloruro de; HI-6. 1-({[4-(Aminocarbonyl)pyridinio]methoxy}methyl)-2-[(hydroxyimino)methyl]pyridinium dichloride.
Chemical formula: C14H16Cl2N4O3 = 359.2.
CAS — 34433-31-3.

Profile

Asoxime chloride is a cholinesterase reactivator that has been tried in the treatment of poisoning by organophosphorus pesticides and related compounds, including nerve agents.
1. Jovanović D, et al. A case of unusual suicidal poisoning by the organophosphorus insecticide dimethoate. Hum Exp Toxicol 1990; 9: 49–51
2. Kušić R, et al. HI-6 in man: efficacy of the oxime in poisoning by organophosphorus insecticides. Hum Exp Toxicol 1991; 10: 113–18.
Published October 15, 2018.