Triflupromazine Hydrochloride

Synonyms: Fluopromazine Hydrochloride; Hidrocloruro de triflupromazina; Triflupromazine, Chlorhydrate de; Triflupromazini Hydrochloridum.
Cyrillic synonym: Трифлупромазина Гидрохлорид.

💊 Chemical information

Chemical formula: C18H19F3N2S,HCl = 388.9.
CAS — 1098-60-8.
ATC — N05AA05.
ATC Vet — QN05AA05.


In US.

USP 31

(Triflupromazine Hydrochloride). A white to pale tan crystalline powder having a slight characteristic odour. Soluble 1 in less than 1 of water and of alcohol and 1 in 1.7 of chloroform; soluble in acetone; insoluble in ether. Store in glass containers. Protect from light.

💊 Profile

Triflupromazine hydrochloride is a phenothiazine with general properties similar to those of chlorpromazine. It is used mainly in the management of psychoses and the control of nausea and vomiting. Triflupromazine hydrochloride is usually given by injection but in some countries oral preparations are available. In the management of psychosis, the usual dose is 60 to 150 mg daily by intramuscular injection. For the control of nausea and vomiting 5 to 15 mg is given intramuscularly and repeated after 4 hours if necessary up to a maximum of 60 mg daily; a dose of 1 mg to a maximum total daily dose of 3 mg may be given intravenously. A suggested intramuscular dose for children over 2 ⁄ years of age is 200 to 250 micrograms/kg daily up to a maximum of 10 mg daily. Reduced doses should be used in elderly or debilitated patients.

💊 Preparations

USP 31: Triflupromazine Hydrochloride Injection; Triflupromazine Hydrochloride Tablets; Triflupromazine Oral Solution.

Proprietary Preparations

Austria: Psyquil; Ger.: Psyquil†; India: Siquil.
Published March 12, 2019.