💊 Chemical information
Dicloralfenazona; Dikloraalifenatsoni; Dikloralfenazon.
Chemical formula: C15H18Cl6N2O5 = 519.0.
CAS — 480-30-8.
ATC — N05CC04.
ATC Vet — QN05CC04.
USP 31(Dichloralphenazone). A white microcrystalline powder with a slight odour characteristic of cloral hydrate. Freely soluble in water, in alcohol, and in chloroform; soluble in dilute acids. It is decomposed by dilute alkalis liberating chloroform.
Dichloralphenazone dissociates when given, to form cloral hydrate and phenazone. It has the general properties of cloral hydrate, although it is less likely to cause gastric irritation after oral doses. Phenazone-induced skin eruptions may, however, occur. Dichloralphenazone is used in some countries in combination preparations mainly for the treatment of tension and vascular headaches.
Porphyria.Dichloralphenazone has been associated with acute attacks of porphyria and is considered unsafe in porphyric patients.
USP 31: Isometheptene Mucate, Dichloralphenazone, and Acetaminophen Capsules. Proprietary PreparationsMulti-ingredient: USA: Duradrin†; Midrin; Migratine†.
Published December 23, 2018.